IMMUNOBIOLOGY Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells
نویسندگان
چکیده
1Department of Dermatology and 2Center for Innovation in Immunoregulative Technology and Therapeutics, Kyoto University Graduate School of Medicine, Kyoto, Japan; 3Department of Animal Development and Physiology, Kyoto University Graduate School of Biostudies, Kyoto, Japan; 4Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan; and 5Laboratory for Autoimmune Regulation and 6Research Unit for Immunodynamics, Research Center for Allergy & Immunology, RIKEN, Yokohama, Japan
منابع مشابه
Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells.
Dendritic cells (DCs) are essential for the initiation of acquired immune responses through antigen acquisition, migration, maturation, and T-cell stimulation. One of the critical mechanisms in this response is the process actin nucleation and polymerization, which is mediated by several groups of proteins, including mammalian Diaphanous-related formins (mDia). However, the role of mDia in DCs ...
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